• 3 Units

• 2 hrs Theory
• 2 hrs Laboratory

• General

• Physics

• • Physical Pharmacy by Alfred Martin, Sixth edition
  • Experimental pharmaceutics by Eugene, Parott.
  • Tutorial pharmacy by Cooper and Gunn.
  • Stocklosam J. Pharmaceutical calculations, Lea &Febiger, Philadelphia.
  • Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3, Marcel Dekkar Inc.
  • Remington: the science and practice of pharmacy, 20th edition, A. Gennaro, Lippincott, last edition.Course Description:   (وصف المقرر)

    Brief Description:

    This course involves the study of the mathematical preparation, states of matter. This includes study of phase rule, interfacial phenomena, solutions and solubility, determination of partition coefficient, and study of solutions properties. Also covers the study of buffered and isotonic solution, rheology and colloids. Theory and practical components of the subject help the student to get a better insight into various areas of formulation research and development, and stability studies of pharmaceutical dosage forms.

    Course Objectives:

    Upon the completion of the course student shall be able to: Understand various physicochemical properties of States of matter. Know the principles of phase equilibrium and phase rule, solutions of non- electrolytes, adsorption, solubility, buffers and isotonic solutions and rheology. Differentiate surface and interfacial tension; describe methods of determination of surface/interfacial laws; describe the solubilization phenomenon. Understanding   the   characteristic, types   of   solutions, colloids and Incompatibility.

    Generic Skills:

    The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of their lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

    Attendance Expectations:

    Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

     Content Breakdown:

    SessionWeek	Topical Coverage
    Session 1(Week 1)	Unit I: Mathematical preparation: •         Units •         Dimensions and statistical analysis of errors Unit II: States of matter: •         Liquid state, vapor pressure, boiling point, surface tension
    Session 2 (Week 2)	•         Solid state. •         Crystalline and amorphous state, crystal systems habits and imperfections. •         Polymorphism, hydrates, other solvates, clathrates and hygroscopicity. •         Melting point and x-ray diffraction.
    Session 3 (Week 3)	Unit III: Micrometrics: •         Definition & significance of particle size, particle size distribution •         Particle size analysis and separation •         Determining particle size shape and surface area
    Session 4 (Week 4)	•         Calculation of particle porosity and density •         Flow property of powder (Hausner ratio, Carr’s index, Angle of repose).
    Session 5 (Week 5)	Unit IV: The phase rule: •         One, two and three component systems. •         One, two and three component systems. •         Eutectic mixtures, solid solutions and glass solutions.
    Session 6 (Week 6)	Unit V: Interfacial phenomena: •         Classification of interfaces. •         Intermolecular forces. •         Surface tension and surface free energy. •         Interfacial tension. •         Measurement of surface and interfacial tension. a.  Capillary rise method. b.  Du nouytensiometer.
    Session 7 (Week 7)	•         Adsorption as liquid interfaces. a.  Surface active agents. b.  HLB system.
    Session 8 (Week 8)	•         Types of monolayers at liquid surfaces. •         Liquid/vapor system, Liquid/liquid system. •         Adsorption at solid interfaces: Solid / liquid interfaces. •         Factor affection the extent of adsorption. •         Longmuir adsorption isotherm, Freundlich adsorption isotherm, Brunaure, Emmett, and taller.
    Session 9 (Week 9)	•         Electric properties of interfaces. •         The electric double layer. •         Nernst zeta potentials.
    Session 10 (Week 10)	Unit VI: Solution and solubility: •         Definition. •         Solubility expressions. •         Solubility of liquids. •         Complete miscibility. •         Partial miscibility.
    Session 11 (Week 11)	Midterm Assessment
    Session 12 (Week 12)
    Session 13 (Week 13)
    Session 14 (Week 14)
    Session 15 (Week 15)	•         Extended Hildebrand solubility approach. •         Solubility parameters. •         Solubility of salts in water. •         Solubility of slightly water-soluble electrolytes. •         Solubility of weak electrolytes.
    Session 16 (Week 16)	•         Calculating of the solubility of weak electrolytes influenced by pH. •         Influence of solvents on solubility of drug. •         Combined effect of pH and solvents. •         Influence of complexation and particle size
    Session 17 (Week 17)	Unit VII: Distribution of solutes between immiscible solvent: •         Determination of partition coefficient. •         Effect of ionic dissociation and molecular association on partition coefficient
    Session 18 (Week 18)	•         Solubility and partition coefficient. •         Extraction. •         Preservative action of weak acids in oil-water system. Drug action and partition coefficient.
    Session 19 (Week 19)	Unit VIII: Colligative properties of solutions:  •         Vapor pressure. •         Boiling point. •         Freezing point. •         Osmotic pressure. •         Diffusion. •         Osmosis. •         M. Wt. Determination. •         Choice of colligative properties.
    Session 20 (Week 20)	Unit IX: Buffered and isotonic solution: •         Definition, buffer equation (for weak acid and base). •         Drugs as buffers, buffer capacity, pharmaceutical buffers, tissue irritation.
    Session 21 (Week 21)	•         Buffered isotonic solutions, measurement of tonicity, methods of adjusting tonicity and pH.
    Session 22 (Week 22)	Unit X: Rheology: •         Newtonain systems. •         Non-Newtonian systems. •         Thixotropy •         Determination of rheological properties. •         Applications to pharmacy.
    Session 23 (Week 23)	Unit XI: Polymers: ·     Definition and classification of polymers. ·     Properties of polymers. ·     Pharmaceutical applications of polymers. ·     Behavior of polymers in solution (effect on viscosity, gel formation, heterogels, syneresis, estimation of molecular weight).
    Session 24 (Week 24)	·         Plasticization of polymers, glass transition temperature, the behavior of polymers during dissolution testing, aging of polymers.
    Session 25 (Week 25)	Unit XII: Colloids: ·         Definition of colloid. ·         Types of colloidal system. ·         Preparation of colloids, ·         Pharmaceutical applications of colloids.
    Session 26 (Week 26)	·         Kinetic properties of colloids. a)       Brownian motion. b)      Diffusion. c)       Sedimentation. d)      Viscosity. e)      Properties of colloids, (electrical, optical, osmotic properties, and particle size).
    Session 27 (Week 27)	•         Electrokinetic phenomena. •         Donnan membrane equilibrium. •         Stability of colloidal systems. Unit XIII: Incompatibility: •         Definition. •         Types of physical incompatibilities.
    Session 28 (Week 28)	•         Types of chemical incompatibilities. •         Factors affecting incompatibility. •         Prevention of incompatibility.
    Practical work	The purpose of the laboratory in this course is to provide students with: ·         Identification of laboratory apparatus and specific techniques which are essential in understanding this course and how to Improve report writing skills. ·         Analysis of Errors. ·         Ternary phase diagram. ·         Intermolecular binding forces. ·         Determination of surface tension of given liquids. ·         Determination the solubility of drug at room temperature. ·         Solubility of benzoic acid in water. ·         The effect of Tween 80 on the solubility of benzoic acid in water. ·         Determination of viscosity using Stoke’s equation. ·         Determination of partition coefficient of benzoic acid in benzene and water. ·         Evaluation of the particle size of solids and measure their flowability. ·         Methods of improving the flowability of solids. ·         Estimation of the molecular weight of polymers. ·         Prediction of the shelf life of dosage forms. ·         Determination of % composition of NaCl in a solution using phenol-water system by CST method ·         Determination of pKa value by Half Neutralization/ Henderson Hasselbalch equation.

     Delivery:   

    • Lectures (Tools: board, data show). The lectures were added on the internet site of the faculty to be available to the students all the time as an e-learning.
    • Practical Session (Tools: labs., boards, instruments, chemicals, glassware, equipment).
    • Assignments, seminars, research and posters.

     Course Assessments:

    • 20% Midyear exam
    • 10% Quizzes, reports, presentation
    • 10% Practical continuous assessment, exam
    • 20% Final Practical exam
    • 40% Final theoretical exam
    • 100% Total

     Textbooks:

• 4 Units

• 3 hrs Theory
• 2 hrs Laboratory

• Specialty

• –

• • • C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott Williams and Walkins, New Delhi.
    • Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, C publishers, New Delhi.
    • E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone, Edinburgh.
    • British pharmacopoeia.

      Course Description:   (وصف المقرر)

      Brief Description:

      This course is designed to impart fundamental knowledge on the preparatory pharmacy with the arts and science of preparing the different conventional dosage forms. The students will study in this subject the history of pharmacy and Orientation to Pharmacy, technique of weighing, concept of pre-formulations, and formulation, pharmaceutical systems, and techniques of measurements. Also, the course covers other topics as pharmaceutical calculations, introduction to dosage forms, pharmaceutical solutions and suspension, and Clinical preparations.

      Course Objectives:

      Upon completion of this course the student should be able to: Know the history of profession of pharmacy. Understand the basics of different dosage forms, pharmaceutical calculations and technique of weighing. To understanding the concept of pre-formulations and formulation. Understand the pharmaceutical solutions and suspensions. Preparation of various conventional dosage forms.

      Generic Skills:

      The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of them lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

      Attendance Expectations:

      Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

       Content Breakdown:

      Content BreakdownWeek	Topical Coverage
      Session 1 (Week 1)	Unit I: History of pharmacy: •         Introduction to drug and pharmacy •         The influence of Arabic civilization in the development of Pharmacy •         The role of Arabic scientists in the development of pharmacy
      Session 2 (Week 2)	Unit II: Orientation to Pharmacy: •         Introduction to the subject of pharmaceutics •         Pharmacy as profession (Hospital, Retail, Industry) •         The role of the pharmacist in the health care system •         The relationship between pharmacist and other health care professionals •         Reviewing and dispensing prescriptions and medication order •         Labeling of dispensed medications •         Computer labeling •         Scope of pharmaceutics
      Session 3 (Week 3)	Unit III: Technique of weighing: •         Description of prescription balance •         Care and use of prescription balance •         Weighing of small doses (Aliquot method of weighing)
      Session 4 (Week 4)	Unit IV: Concept of pre-formulations and formulation: •         Biopharmaceutical and therapeutic considerations in dosage form  design. •         Drug incompatibility: (Physical, Chemical, Pharmacokinetics, and Pharmacodynamic).
      Session 5 (Week 5)	•         Introductory aspects of physicochemical properties with their applications.
      Session 6 (Week 6)	•         Pharmaceutical recipients: solvents, colorants, flavors, diluents, binders, disintegrants, lubricants, thickening agents, emulsifying agents, etc.
      Session 7 (Week 7)	Unit V: Pharmaceutical systems and techniques of measurements: •         Common systems, Weights, and measures – Imperial & Metric system, ( units and terminology, CGS, FFs, units of mass, units of •         amount of substance, units of length, units of radiation, dose equivalent) •         The relationship and unit conversions of systems
      Session 8 (Week 8)	Unit VI: Pharmaceutical calculations: •         General dilutions: using stock solutions, allegation method, least weighable amounts/percentage error
      Session 9 (Week 9)	•         The calculation of dose: Miscellaneous dosage problem, •         calculation of doses of children. •         Calculation of body surface area.
      Session 10 (Week 10)	•         Reducing and enlarging formulas
      Session 11 (Week 11)	Midterm Assessment
      Session 12 (Week 12)
      Session 13 (Week 13)
      Session 14 (Week 14)
      Session 15 (Week 15)	·         Density and specific gravity: sp. Gravity of liquids and solids, calculation of volume and weight from sp. Gravity
      Session 16 (Week 16)	·         Ratio strength and stock solutions
      Session 17 (Week 17)	Unit VII: Introduction to dosage forms: ·         Short description and properties of different dosage forms
      Session 18 (Week 18)	·         The need for dosage forms ·         Therapeutic consideration in dosage form design
      Session 19 (Week 19)	·         Routes of drug administration: Oral, parentral, rectal, nasal, etc.
      Session 20 (Week 20)	Unit VIII: Pharmaceutical solutions: ·         Introduction ·         Advantages and disadvantages
      Session 21 (Week 21)	·         Aqueous solutions: Standards for water, aromatic waters, aqueous acids, solutions douche, enemas, gargles, mouth washes, juices, ·         sprays, syrups, honey, optic solutions, irrigations, toothache drops
      Session 22(Week 22)	·         Aromatic waters: Types and method of preparation ·         Non-aqueous solutions: Elixirs, spirits, collodious, liniments, tinctures, mucilages ·         proof spirit and isotonic solutions ·         Pharmaceutical solvents: glycol, alcohol, etc.
      Session 23 (Week 23)	Unit IX: Pharmaceutical Suspension: ·         Definition. ·         Advantages of oral suspensions. ·         Classification based on type of preparation and route of administration
      Session 24 (Week 24)	·         Types of suspensions. ·         Manufacturing
      Session 25 (Week 25)	·         Sedimentation rate and factors affecting it. ·         Evaluation of stability of suspension
      Session 26 (Week 26)	Unit X: Clinical preparations: ·         Principle and methods of preparation: infusion, decoction, maceration, percolation.
      Session 27 (Week 27)	·         Principle and methods of preparation: infusion, decoction, maceration, percolation.
      Session 28 (Week 28)	·         Principle and methods of preparation: infusion, decoction, maceration, percolation.
      Practical work	Practical Part: ·         identification of laboratory apparatus ·         pharmaceutical calculations ·         chloroform water ·         peppermint water ·         aqueous iodine solution ·         weak iodine solution ·         orange tincture ·         simple syrup ·         orange syrup ·         camphor liniment ·         Ferrous sulphate mixture

       Delivery:     

      • Lecture-based, Group interaction and discussion.
      • Use of video technique, practical classes.

      Course Assessments:

      • 20% Assessment Exam
      • 10% in lab activities
      • 10% in class activities e.g.: quizzes
      • 40% Final theoretical exam
      • 20 % Final Practical Exam
      • Total 100%

      Textbooks:

    • C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott Williams and Walkins, New Delhi.
    • Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, C publishers, New Delhi.
    • E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone, Edinburgh.
    • British pharmacopoeia.

• 3 Units

• 2 hrs Theory
• 2 hrs Laboratory

• Specialty

• Pharmaceutics I

• • • Course Description:   (وصف المقرر)

      Brief Description:

      This course is designed to impart a fundamental knowledge on the preparatory pharmacy with arts and science of preparing the different conventional dosage forms.

      Course Objectives:

      Upon completion of this course the student should be able to: Know the history of profession of pharmacy. Understand the basics of different dosage forms, pharmaceutical incompatibilities and pharmaceutical calculations Understand the professional way of handling the prescription Preparation of various conventional dosage forms

      Generic Skills:

      The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of their lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

      Attendance Expectations:

      Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

       Content Breakdown:

      Content BreakdownWeek	Topical Coverage
      Session 1 (Week 1)	Unit I. Emulsions: •         Definition. •         Purposes of emulsification. •         Theories of emulsification.
      Session 2 (Week 2)	•         Types of emulsifying agents. •         Tests for determination of emulsion type.
      Session 3 (Week 3)	•         Preservation of emulsions. •         Manufacturing.
      Session 4 (Week 4)	Unit II: Semi – solid dosage forms: a)  Ointments: •         Definition. •         Function of ointments and ointments bases Excipients used in semi solid dosage forms. Evaluation of semi solid dosage forms. •         Release rate of semi-solid dosage form.
      Session 5 (Week 5)	•         Classification of ointments bases.
      Session 6 (Week 6)	•            Considerations in compounding and dispensing, e.g., quality, suitability
      Session 7 (Week 7)	b)  Creams and gels: •         Types of creams and gels. •         Formulation. •         Filling and Packaging. •         Type of base & Functions.
      Session 8 (Week 8)	•         Packaging.
      Session 9 (Week 9)	•         Type of base & Functions.
      Session 10 (Week 10)	c)  Suppositories: •         History •         Types and therapeutic uses, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.
      Session 11 (Week 11)	Midterm Assessment
      Session 12 (Week 12)
      Session 13 (Week 13)
      Session 14 (Week 14)
      Session 15 (Week 15)	•         Anatomy of rectum & factors affecting drug absorption
      Session 16 (Week 16)	•         Classification of suppository bases •         General consideration of compounding & dispensing •         Manufacturing, packaging, evaluation and stability of semidolid dosage forms.
      Session 17 (Week 17)	Unit III: Modified-release Pharmaceutical Dosage forms (MRPD): •         Pharmaceutical Concepts. •         Formulation of (MRPD).
      Session 18 (Week 18)	•         Mechanisms of drug release from MRPD.
      Session 19 (Week 19)	Unit IV: Complexation and protein binding: •         Definitions and Introduction. •         Types of complexes.
      Session 20 (Week 20)	•         Types of complex reactions. •         Methods of complex analysis.
      Session 21 (Week 21)	•         Protein binding. •         Equilibrium dialysis.
      Session 22 (Week 22)	•         Dynamic dialysis.
      Session 23 (Week 23)	•         Complexation and drug action.
      Session 24 (Week 24)	Unit V:  Kinetics: •         Rate and order of reactions. •         Determination of order of reactions. •         Factors influencing the reaction rate.
      Session 25 (Week 25)	Unit VI: Product stability: •         Factors affecting drug stability. •         Reactions causing drug decompositions.
      Session 26 (Week 26)	•         Types of stability tests. •         Prediction of shelf life and expiry dates.
      Session 27 (Week 27)	•         Stability tests of pharmaceutical dosage forms.
      Session 28 (Week 28)	•         Stabilization of pharmaceutical products
      Practical Part:	Practical Part: •         Preparation of arachis oil emulsion •         Preparation of liquid paraffin emulsion •         Preparation of calamine lotion •         Preparation of salicylic acid lotion •         Preparation of aminobenzoic acid lotion •         Preparation of lubricating jelly •         Preparation of zinc oxide paste •         Preparation of vanishing cream •         Preparation of cold cream •         Preparation of suppositories using theobroma oil and displacement value (calculation (theoretical) •         Preparation of suppositories using glycerol-gelatin base and displacement value (calculation (theoretical) •         Determination of rate, rate constant and half-life of zero order reaction (theoretical) •         Determination of rate, rate constant and half-life of first order reaction •         (theoretical)

       Delivery:     

      Lecture-based, Group interaction and discussion, Use of video technique, practical classes.

      Course Assessments:

      • 20% Assessment Exam
      • 10% in lab activities
      • 10% in class activities e.g.: quizzes, reports, discussion…
      • 40% Final theoretical exam
      • 20 % Final Practical Exam
      • Total 100%

      Textbooks:

      • Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott Williams, New Delhi.
      • Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
      • A. Rawlins, Bentley’s Textbook of Pharmaceutics, English Language Book Society, Elsevier Health Sciences, USA.
      • Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC, New York.
      • Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker, INC, New York.

      Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and Suspensions, Marcel Dekker, INC, New York.

• 4 Units

• 3 hrs Theory
• 2 hrs Laboratory

• Specialty

• Pharmaceutics I

• • • Course Description:   (وصف المقرر)

      Brief Description:

      This course focuses on the study of the interrelationships between formulation and physiological factors and pharmacokinetic aspects of drug absorption, distribution, metabolism, and excretion.

       Course Objectives:

      Upon completion of the course, the student shall be able to: To have the expertise and knowledge needed to be involved in different pharmaceutical care settings in community pharmacies, industrial sector, pharmaceutical sales and marketing. Supplying information about pharmaceutical packaging, GMP, validation, contamination, sterilization and pharmaceutical plant. Supplying information about aerosol.

       Generic Skills:

      The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of their lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

      Attendance Expectations:

      Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

       Content Breakdown:

      Content BreakdownWeek	Topical Coverage
      Session 1 (Week 1)	Size reduction and size separation: (powder, granulation technology) •     Definitions, factors affecting size reduction •     Principles, laws and factors affecting energy requirements
      Session 2 (Week 2)	•    Methods of size reduction •    Hammer mill, fluid energy mill and disintegrator.
      Session 3 (Week 3)	•    Size separation: various methods and equipments employed for size separation: e.g., sieving, sedimentation, centrifugal elutriation microscopic methods… etc. •    Pelletization.
      Session 4 (Week 4)	•    Dust control
      Session 5 (Week 5)	Safety measuring and industrial hazards
      Session 6 (Week 6)	Introduction to production management
      Session 7 (Week 7)	Heat transfer
      Session 8 (Week 8)	Evaporation
      Session 9 (Week 9)	Drying
      Session 10 (W- 10)	•    Drying continue.
      Session 11 (Week 11)	Midterm Assessment
      Session 12 (Week 12)
      Session 13 (Week 13)
      Session 14 (Week 14)
      Session 15 (Week 15)	Mass transfer and fluid mechanics
      Session 16 (Week 16)	Filtration Centrifugation
      Session 17 (Week 17)	Crystallization Mixing
      Session 18 (Week 18)	Pharmaceutical Packaging Technology
      Session 19 (Week 19)	Topical and transdermal drug delivery techniques
      Session 20 (Week 20)	Pulmonary drug delivery techniques (Aerosols)
      Session 21 (Week 21)	Pharmaceutical nanotechnology and nanomedicines
      Session 22 (Week 22)	Sterile products
      Session 23 (Week 23)	Pilot plane and scale up
      Session 24 (Week 24)	Structure of pharmaceutical plan
      Session 25 (Week 25)	Surgical ligature
      Session 26 (Week 26)	Current good manufacturing practice
      Session 27 (Week 27)	•    Current good manufacturing practice
      Session 28 (Week 28)	Manufacturing authorization and product registration
      Practical Work:	•    preparation of simple ointment and Sulphur ointment. •    preparation of emulsifying ointment and Whitfield ointment. •    preparation of non-staining iodine ointment •    preparation of vanishing cream •    preparation of cold cream •    preparation of salicylic acid and sulphuric cream •    preparation of cetrimide cream •    preparation of tragacanth jelly •    preparation of boric acid suppositories •    preparation of zinc oxide suppositories •    preparation of toothpaste •    solubility curves •    calculation of filter media resistance and cake resistance •    rate of sedimentation •    particle size analysis.

       Delivery:     

      • Lecture-based, Group interaction and discussion,
      • Self-directed activities
      • Active participation,
      • Computer lab
      • Lab experiments

      Course Assessments:

      • 20% Assessment Exam
      • 10% Quizzes, reports, ….
      • 10% Lab classes and activities
      • 20% Final Lab exam
      • 40% Final theoretical exam
      • 100% Total

       Textbooks:

      • Remington’s pharmaceutical sciences
      • Aulton’s pharmaceutics
      • Sciences direct web

       

• 4 Units

• 3 hrs Theory
• 2 hrs Laboratory

• Specialty

• Pharmaceutics I & II
•  Physical Pharmacy

Course Description:   (وصف المقرر)

Brief Description:

This course focuses on the study of the interrelationships between formulation and physiological factors and pharmacokinetic aspects of drug absorption, distribution, metabolism, and excretion.

Course Objectives:

Upon completion of the course student should be able to: Understand the basic concepts in biopharmaceutics and pharmacokinetics and their significance. Use of plasma drug concentration-time data to calculate the pharmacokinetic parameters to describe the kinetics of drug absorption, distribution, metabolism, excretion, elimination. To understand the concepts of bioavailability and bioequivalence of drug products and their significance. Understand various pharmacokinetic parameters, their significance & applications.

 Generic Skills:

The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of their lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

Attendance Expectations:

Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

 Content Breakdown:

 Delivery:     

• Lecture-based, Group interaction and discussion,
• Self-directed activities
• Active participation
• Computer lab
• Lab experiments …..etc

 Course Assessments:

• 20% Assessment Exam
• 10% Quizzes, reports, ….
• 10% Lab classes and activities
• 20% Final Lab exam
• 40% Final theoretical exam
• 100% Total

 Textbooks:

• Leon Shargel, Andrew B.C. Yu, eds. Applied Biopharmaceutics and Pharmacokinetics, 7th edition. New York: McGraw Hill, 2016. ISBN: 978-0-07- 183093-5.
• Derendorf, Hartmut; Schmidt, Stephan. Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics – Concepts and Applications, 5th Ed, Walters-Kluwer: 2020, ISBN: 978-1-49-638504-8.
• Principles and Applications of Biopharmaceutics and Pharmacokinetics: for Pharmacy. Late Dr. H.P Tipnis and Dr. Amrita Bajaj ISBN: 8188739146, 9788188739141

Additional Resources:

• Lecture slides
• Microsoft Office Excel software with PK Solver tool Winnonlin or Phoenix Software
• Small ruler and scientific calculator or laptop calculator/calculation tool (in class)
• Rectilinear and semi logarithmic graph papers

• 4 Units

• 3 hrs Theory
• 2 hrs Laboratory

• Specialty

• Pharmaceutics I & II

Course Description:   (وصف المقرر)

Brief Description:

The course deals with the basic pharmaceutical operations that take place in the pharmaceutical industry, as well as how to establish a pharmaceutical factory. The course also focuses in the devices industry. Course enables the student to understand and appreciate the influence of pharmaceutical additives and various pharmaceutical dosage forms on the performance of the drug product.

Course Objectives:

Upon completion of the course student should be able to: Know the various pharmaceutical dosage forms and their manufacturing techniques. Understand the process of technology transfer from lab scale to commercial batch. Know various considerations in development of pharmaceutical dosage forms. Formulate solid, liquid and semisolid dosage forms and evaluate them for their quality.

 Generic Skills:

The faculty is committed to ensuring that students have the full range of knowledge and skills required for full participation in all aspects of their lives, including skills enabling them to be life-long learners. To ensure graduates have this preparation, such generic skills as literacy and numeric, computer, interpersonal communications, and critical thinking skills will be embedded in all courses.

Attendance Expectations:

Students are expected to attend every session of class, arriving on time, returning from breaks promptly and remaining until class is dismissed. Absences are permitted only for medical reasons and must be supported with a doctor’s note.

 Content Breakdown:

 Delivery:     

• Lectures (Tools: board, data show). The lectures were added on the internet site of the faculty to be available to the students all the time as an e-learning.
• Practical Session (Tools: labs., boards, instruments, chemicals, glassware, equipment).
• Assignments, seminars, research and posters.

Course Assessments:

• 20% Midyear Examination
• 10% Practical continuous Assessment, Exam
• 10% Quiz, reports, presentation
• 20% Final practical Examination
• 40% Final written Examination
• 100% Total

 Textbooks:

• Modern Pharmaceutics by Gilbert S. Banker & C.T. Rhodes, 3rd Edition
• Remington: The Science and Practice of Pharmacy, 20th edition Pharmaceutical Science (RPS)
• Theory and Practice of Industrial Pharmacy by Liberman & Lachman
• Pharmaceutics- The science of dosage form design by M.E. Aulton, Churchill Livingstone, Latest edition
• Additional Resources: Lectures Notes

• 2 Units

• 2 hrs Theory

• Specialty

• –

Course Description:   (وصف المقرر)

Brief Description:

يحتوي منهج المحاسبة التعريفات والأهداف والمصطلحات المحاسبية، ومعادلة الميزانية، كذلك الدورة المحاسبية بخطواتها بشكل مختصر وقد تم التطرق إلى بعض الأمثلة الافتراضية عن عمليات البيع والشراء لشكات الأدوية والصيدليات حتى يسهل استيعاب الدورة لدى طالب الصيدلة. والجزء الثاني إدارة الأعمال الصيدلية حيث يسلط الضوء على عمليات التسويق والدعاية والتسعير، وأيضا دراسة اتفاقية الجات سنة 1994 وأثارها الإيجابية والسلبية، والتي ركزت على تجارة الأدوية وأثر هذه الاتفاقية على الدول النامية. كما تم دراسة الرقابة على شركات الأدوية، وتقييم الأداء المالي، ومشاكل التسويق والإنتاج والجودة ومستقبل شركات الأدوية في القرن الواحد والعشرين، والفرق بين شركات الأدوية العربية والأجنبية.

Course Objectives:

بدراسة المقرر سيكون الطالب قد أثبت بشكل موثوق القدرة على: فهم الدورة المحاسبية ومشاكل شركات الأدوية ووضع الحلول المقترحة. كيفية تحديد الأرباح لدى شركات الأدوية وتقييمها. التعرف على مجالات الرقابة الدوائية ومستقبل شركات الأدوية العربية. تحديد المشكلة والأحكام والشروط عند استيراد الأدوية وتخزينها. تطوير مهارات الطالب في عمليات البيع والشراء في شركات الأدوية والصيدليات ومعرفة العمليات المدينة والدائنة.

 Generic Skills:

تلتزم الكلية بضمان حصول الطلاب على كامل المعرفة والمهارات اللازمة للمشاركة الكاملة في جميع جوانب حياتهم، بما في ذلك المهارات التي تمكنهم من أن يكونوا متعلمين مدى الحياة، لضمان حصول الخريجين على هذا الإعداد، سيتم تضمين مهارات عامة مثل الكمبيوتر والاتصالات الشخصية ومهارات التفكير.

Attendance Expectations:

يجب على الطلاب حضور كل المقرر الدراسي في الوقت المحدد، ولا يسمح بالتغيب إلا لأسباب طبية ويجب دعمه بتقرير طبي.

 Content Breakdown:

 Delivery:     

• المحاضرات
• التفاعل والنقاش الجماعي
• الأنشطة الموجهة ذاتيا.
• المشاركة النشطة

 Course Assessments:

• 40% الامتحان النصفي
• 60% الامتحان النهائي
• 100% المجموع

 Textbooks:

• مبادئ المحاسبة، إدريس اشتيوي.
• إدارة الأعمال الصيدلية، محمد أحمد بغدادي
• إدارة المستشفيات وشركات الأدوية، فريد النجار